Recombinant Human Anti-human CR1 Antibody (CAT#: MHH-240)
Recombinant Human Antibody has specificity for an antigen Human CR1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CR1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CR1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
Figure 3 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
Figure 4 RNA cell line category: Group enriched (HL-60, HMC-1, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
Specifications
- Immunogen
- Human complement component (3b/4b) receptor 1 (Knops blood group)
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human complement component (3b/4b) receptor 1 (Knops blood group)
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Enzyme-linked Immunosorbent Assay; Immunoprecipitation; Functional Study
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- CR1; complement component (3b/4b) receptor 1 (Knops blood group); KN; C3BR; C4BR; CD35; complement receptor type 1; C3-binding protein; C3b/C4b receptor; CD35 antigen; Knops blood group antigen
- Gene ID
- 1378
- UniProt ID
- P17927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "CR1"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240-F(E) | Recombinant Anti-human CR1 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-240-F(E) | Recombinant Human Anti-human CR1 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0421-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone E11); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0422-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); Fab Fragment | ELISA, FC | Mouse Fab |
| FAMAB-0310-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone HB8592); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240-S(P) | Recombinant Anti-human CR1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-0421-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone E11); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0422-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0423-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0424-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone EDI3G4); scFv Fragment | ELISA, FC | Mouse scFv |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-496CQ | Mouse Anti-CR1 Recombinant Antibody (clone J3D3) | Block, ELISA, FC, IHC-Fr, IHC-P | Mouse IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0794 | Hi-Affi™ Rabbit Anti-CR1 Recombinant Antibody (clone DS794AB) | WB, IHC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1102CQ | Mouse Anti-CR1 Recombinant Antibody (clone 8C12) | FC | Mouse IgG1 |
| FAMAB-1103CQ | Human Anti-CR1 Recombinant Antibody (clone E11) | IF, IP | Human IgG1 |
| ZG-0107J | Mouse Anti-CR1 Recombinant Antibody (ZG-0107J) | IHC-P, IF | Mouse IgG |
| ZG-0108J | Mouse Anti-CR1 Recombinant Antibody (ZG-0108J) | IHC-P, IF | Mouse IgG |
| ZG-0621J | Rabbit Anti-CR1 Recombinant Antibody (clone 9A9) | ELISA, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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