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  • Recombinant Human Anti-human SCN9A Antibody

Recombinant Human Anti-human SCN9A Antibody (CAT#: MHH-891)

Recombinant Human Antibody exhibits selective binding affinity to Human SCN9A, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SCN9A mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SCN9A mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.


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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line BJ
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to plasma membrane, actin filaments & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/61843/1332_D6_5_selected.jpg
Figure 2 IHC staining of human colon
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_8_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HHSteC, hTERT-RPE1)
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HHSteC, hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169432-SCN9A/subcellular

Specifications

  • Immunogen
  • Human sodium channel, voltage gated, type IX alpha subunit
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native Human sodium channel, voltage gated, type IX alpha subunit
  • Species Reactivity
  • Human
  • Applications
  • Formats of immunological tests: Western blot; Neutralization; Functional Study

Product Property

  • Purity
  • >95% by HPLC
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • SCN9A; sodium channel, voltage gated, type IX alpha subunit; PN1; ETHA; NENA; SFNP; FEB3B; NE-NA; GEFSP7; HSAN2D; Nav1.7; sodium channel protein type 9 subunit alpha; hNE-Na; peripheral sodium channel 1; neuroendocrine sodium channel; sodium channel prote

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "SCN9A"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-891-F(E) Recombinant Anti-human SCN9A Antibody Fab Fragment ELISA, RIA, FuncS Fab
MHH-891-F(E) Recombinant Human Anti-human SCN9A Antibody Fab Fragment WB, ELISA, FuncS Fab
HPAB-0052-FY-F(E) Rabbit Anti-SCN9A Recombinant Antibody; Fab Fragment (HPAB-0052-FY-F(E)) ELISA Rabbit Fab
HPAB-0109-WJ-F(E) Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-F(E)); Fab Fragment ELISA Human Fab
HPAB-0542-FY-F(E) Human Anti-SCN9A Recombinant Antibody (clone 22D04); Fab Fragment ELISA Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-891-S(P) Recombinant Anti-human SCN9A Antibody scFv Fragment ELISA, IP, FuncS scFv
MHH-891-S(P) Recombinant Human Anti-human SCN9A Antibody scFv Fragment WB, IHC, FuncS scFv
HPAB-0052-FY-S(P) Rabbit Anti-SCN9A Recombinant Antibody; scFv Fragment (HPAB-0052-FY-S(P)) ELISA Rabbit scFv
HPAB-0542-FY-S(P) Human Anti-SCN9A Recombinant Antibody (clone 22D04); scFv Fragment ELISA Human scFv
HPAB-0543-FY-S(P) Human Anti-SCN9A Recombinant Antibody (clone 28608); scFv Fragment ELISA Human scFv

Human Antibody

CAT Product Name Application Type
TAB-0334CL Human Anti-SCN9A Recombinant Antibody (TAB-0334CL) FuncS, IHC, Block, Inhib, ELISA Human IgG
TAB-0334CL-S(P) Human Anti-SCN9A Recombinant Antibody; scFv Fragment (TAB-0334CL-S(P)) FuncS, IHC, Block, Inhib, ELISA Human scFv
TAB-0334CL-F(E) Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-0334CL-F(E)) FuncS, IHC, Block, Inhib, ELISA Human Fab
TAB-474MZ-F(E) Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-474MZ-F(E)) ELISA Human Fab
TAB-475MZ-F(E) Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-475MZ-F(E)) ELISA Human Fab

Mouse Antibody

CAT Product Name Application Type
TAB-469MZ-F(E) Anti-Human SCN9A Recombinant Antibody Fab Fragment (8A7) ELISA, FuncS
TAB-470MZ-F(E) Anti-Human SCN9A Recombinant Antibody Fab Fragment (8B6) ELISA, FuncS
TAB-471MZ-F(E) Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A1) ELISA, FuncS
TAB-472MZ-F(E) Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A6) ELISA, FuncS
TAB-473MZ-F(E) Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A11) ELISA, FuncS

Neuroscience Antibody

CAT Product Name Application Type
NS-053CN Mouse Anti-SCN9A Recombinant Antibody (NS-053CN) ELISA, Block, FuncS Mouse IgG1
NS-053CN-F(E) Mouse Anti-SCN9A Recombinant Antibody; Fab Fragment (NS-053CN-F(E)) ELISA Mouse Fab
NS-053CN-S(P) Mouse Anti-SCN9A Recombinant Antibody; scFv Fragment (NS-053CN-S(P)) ELISA Mouse scFv

Recombinant Antibody

CAT Product Name Application Type
HPAB-0052-FY Rabbit Anti-SCN9A Recombinant Antibody (HPAB-0052-FY) ELISA Rabbit IgG1
MRO-1062-CN Recombinant Mouse Anti-SCN9A Monoclonal Antibody (1D6) IHC, IF, FC, WB Mouse IgG2b
MRO-2056-CN Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2056-CN) IF, IHC, FC Rabbit IgG
MRO-2057-CN Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2057-CN) IF, IHC Rabbit IgG
HPAB-0109-WJ Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ) ELISA Human IgG4, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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