Recombinant Mouse Anti-Human ITGB2 Antibody F(ab')2 Fragment, clone IB4 (CAT#: DrMAB-980)
Recombinant Mouse Antibody binds selectively to Mouse ITGB2, expressed in HPB-M.
Specific Inquiry
FC
Figure 1 Competitive binding assay of native murine 1B4 (diaminds) and Gal/Rei humanized 1B4 (circles).
FC
Figure 2 Competitive binding assay of New/Rei recombinant h1B4 (closed diamonds) and Gal/Rei recombinant h1B4 (open diamonds).
Inhib
Figure 3 Dose-dependet inhibition by of m1B4 and Gal/Rei h1B4 of C5a (100 pmol)-induced PMN accumulation in rabbit skin.
Inhib
Figure 4 Inhibition measurement of m1B4 and Gal/Rei h1B4 of C5a (100 pmol)-induced plasma extravasation in rabbit skin.
Specifications
- Immunogen
- Human peripheral blood monocytes
- Host Species
- Mouse
- Type
- F(ab')2
- Specificity
- Antibody reacts the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd.
- Species Reactivity
- Human
- Clone
- IB4
- Applications
- FC, Inhib
Product Property
- Purification
- Protein A purification
- Purity
- >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
- Concentration
- 1 mg/ml
- Buffer
- 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl. Product was sterile filtered and vialed under aseptic conditions. No preservative added
- Storage
- Store at 2-5°C. Open under aseptic conditions.
Applications
- Application Notes
- The ITGB2 antibody has been reported in applications of Flow Cytometry, Inhibition.
Target
- Alternative Names
- ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); CD18, integrin, beta 2 (antigen CD18 (p95), lymphocyte function associated antigen 1; macrophage antigen 1 (mac 1) beta subunit), MFI7; integrin beta-2; LFA 1; MAC 1; integrin beta
- Gene ID
- 3689
- UniProt ID
- B4E0R1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-099 | Recombinant Anti-Human ITGB2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-044 | Anti-Human ITGB2 Recombinant Antibody (Rovelizumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
| TAB-461CL | Human Anti-ITGB2 Recombinant Antibody (TAB-461CL) | ELISA | Human IgG |
| TAB-1582CL | Anti-Human ITGB2 Recombinant Antibody (Hu23F2G (also known as LeukArrest and Rovelizumab)) | IP, FuncS | Humanized antibody |
| TAB-1582CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
| TAB-1582CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1581CL | Anti-Human ITGB2 Recombinant Antibody (23F2G) | Inhib | |
| TAB-1581CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (23F2G) | Inhib | |
| TAB-1581CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (23F2G) | Inhib |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0298MZ | Chicken Anti-ITGB2 Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1590CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-48) | BL, FC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| NEUT-1591CQ | Recombinant Mouse Anti-ITGB2 Antibody (TS1/18) | BL, FC, ICC/IF, IHC, WB | IgG1 |
| NEUT-1592CQ | Recombinant Mouse Anti-ITGB2 Antibody (YFC118.12) | FC, BL | IgG1, κ |
| NEUT-1593CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-148) | FC, IP, WB, BL, FuncS | IgG1 |
| NEUT-1594CQ | Recombinant Hamster Anti-Itgb2 Antibody (2E6) | BL, ICC, IP, FC | IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1884 | Hi-Affi™ Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (DS1884AB) | IP, WB | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-044 | Afuco™ Anti-ITGB2 ADCC Recombinant Antibody (Rovelizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-006CQ | Recombinant Mouse Anti-ITGB2 Antibody (IB4) | FC, Block | Mouse IgG2a |
| FN-007CQ | Mouse Anti-ITGB2 Recombinant Antibody (clone IB4) | FC, Block | Mouse F(ab')2 |
| HPAB-1769-FY | Human Anti-ITGB2 Recombinant Antibody (clone D2-57) | ELISA | Human IgG |
| HPAB-1770-FY | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001) | ELISA | Human IgG |
| HPAB-1771-FY | Human Anti-ITGB2 Recombinant Antibody (clone C1-54) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1769-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); Fab Fragment | ELISA | Human Fab |
| HPAB-1770-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); Fab Fragment | ELISA | Human Fab |
| HPAB-1771-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone C1-54); Fab Fragment | ELISA | Human Fab |
| HPAB-1207WJ-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone pxCD18-7T3); Fab Fragment | ELISA | Human Fab |
| HPAB-1376WJ-F(E) | Human Anti-ITGB2 Recombinant Antibody; Fab Fragment (clone huH52) | ELISA, WB | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1207WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone pxCD18-7T3); scFv Fragment | ELISA | Human scFv |
| HPAB-1292WJ-S(P) | Rat Anti-ITGB2 Recombinant Antibody (clone YFC51.1); scFv Fragment | ELISA, FC | Rat scFv |
| HPAB-1293WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone LDP-01); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-1376WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone huH52) | ELISA, WB | Human scFv |
| HPAB-1569WJ-S(P) | Mouse Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone 1B4) | ELISA, WB, IF | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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