Recombinant Mouse Anti-Human MMP9 Antibody Fab Fragment (CAT#: DrMAB-1048)

Recombinant Mouse Antibody binds selectively to Mouse MMP9, expressed in E. coli.


Specific Inquiry
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  • Conjugation:
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  • Purity:
  • Published Data
  • Gene Expression
  • Datasheet
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  • COA
WB

Figure 1 MMP-9, MMP-2, TIMP-1, and TIMP-2 protein levels were measured using western blot analysis.

Figure 1 MMP-9, MMP-2, TIMP-1, and TIMP-2 protein levels were measured using western blot analysis.

Qin, W., Li, J., Zhu, R., Gao, S., Fan, J., Xia, M., ... & Zhang, J. (2019). Melatonin protects blood-brain barrier integrity and permeability by inhibiting matrix metalloproteinase-9 via the NOTCH3/NF-κB pathway. Aging (Albany NY), 11(23), 11391.

IF

Figure 2 Melatonin pretreatment ameliorates the effect of MMP-9 on the expression of VE-cadherin, occludin, claudin-5, and ZO-1 in the BBB in different treatment groups.

Figure 2 Melatonin pretreatment ameliorates the effect of MMP-9 on the expression of VE-cadherin, occludin, claudin-5, and ZO-1 in the BBB in different treatment groups.

Qin, W., Li, J., Zhu, R., Gao, S., Fan, J., Xia, M., ... & Zhang, J. (2019). Melatonin protects blood-brain barrier integrity and permeability by inhibiting matrix metalloproteinase-9 via the NOTCH3/NF-κB pathway. Aging (Albany NY), 11(23), 11391.

ELISA

Figure 3 DAI and representative H&E-stained colon sections from DSS-treated Mmp9þ/þ and Mmp9-/- colitic mice (right panel) are shown.

Figure 3 DAI and representative H&E-stained colon sections from DSS-treated Mmp9þ/þ and Mmp9-/- colitic mice (right panel) are shown.

Munakata, S., Tashiro, Y., Nishida, C., Sato, A., Komiyama, H., Shimazu, H., ... & Yagita, H. (2015). Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9–Mediated Cytokine Release From Myeloid Cells. Gastroenterology, 148(3), 565-578.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Type
  • Fab
  • Specificity
  • Does not recognize the 67kDa Active form of MMP-9, but does recognize the 82kDa Active form of MMP-9 and pro-MMP-9
  • Species Reactivity
  • Human
  • Applications
  • LMNX, ELISA, WB, IF

Product Property

  • Purity
  • >95% (SDS-PAGE)
  • Concentration
  • 1 to 25 mg/mL (lot-specific)
  • Buffer
  • 50 mM Potassium Phosphate, 10 mM Boric Acid, 150 mM NaCl, pH 7
  • Storage
  • 2-8°C short term, or <-15°C short or long term. Avoid freeze-thaw cycles

Applications

  • Application Notes
  • The Human MMP9 antibody has been reported in applications of LMNX, Enzyme-linked Immunosorbent Assay, Western Blot, Immunofluorescence.

Target

  • Alternative Names
  • MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); CLG4B, matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase), matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa typ

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MMP9"

Humanized Antibody

CAT Product Name Application Type
TAB-533CL Anti-Human MMP9 Recombinant Antibody (GS-5745) WB, Inhib Antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0717MZ Chicken Anti-MMP9 Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1748CQ Recombinant Mouse Anti-MMP9 Antibody (VMC204) Inhib, IHC-Fr, IP, IHC-P, WB, IHC, ICC IgG1

Chimeric Antibody

CAT Product Name Application Type
TAB-002ML Anti-Human MMP9 Recombinant Antibody (Andecaliximab) ELISA, IHC, FC, IP, IF, FuncS IgG4, κ

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-002ML Afuco™ Anti-MMP9 ADCC Recombinant Antibody (Andecaliximab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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