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Anti-Siglec1 antibody, clone 3D6.112 (DrMAB-106)

Recombinant Rat Antibody binds selectively to Rat Siglec1.      

Specifications
Immunogen
Spleen cells from AO rats immunised with thioglycollate-elicted mouse peritoneal macrophages (TPM) that had been cutured in mouse serum to induce sheep erythrocyte receptor (SER).
Host
Rat
Type
IgG
Specificity
This antibody specifically recognize mouse CD169, which is a 180-185-kDa member of the Siglec family of macrophage-specific cell adhesion and endocytic receptors interacting with sialylated glycans. This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow. CD169 can also be detected on monocytes in the bone marrow and periphery.
Clone
3D6.112
Applications
WB
Target
Alternative Names
Siglec1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sn; Cd169; Siglec-1; sialoadhesin; SER; sheep erythrocyte receptor
Entrez Gene ID
20612
UniProt ID
G3X8X6

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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