Recombinant Rat Anti-mouse Itgam Antibody, clone 5C6 (CAT#: DrMAB-104)

Recombinant Rat Antibody binds selectively to Rat Itgam.


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  • Gene Expression
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WB

Figure 1 Macrophages from WT, Clec7a−/−, Clec4n−/− , and Itgam−/− mice were stimulated with or without (0 min) H. capsulatum (MOI = 5) for 30 and 60 min.

Figure 1 Macrophages from WT, Clec7a−/−, Clec4n−/− , and Itgam−/− mice were stimulated with or without (0 min) H. capsulatum (MOI = 5) for 30 and 60 min.

Huang, J. H., Liu, C. Y., Wu, S. Y., Chen, W. Y., Chang, T. H., Kan, H. W., ... & Wu-Hsieh, B. A. (2018). NLRX1 facilitates Histoplasma capsulatum-induced LC3-associated phagocytosis for cytokine production in macrophages. Frontiers in immunology, 9, 2761.


Specifications

  • Immunogen
  • Fusion of spleen cells from AO rats immunised with Thioglycollate-elicted muine peritoneal macrophages (TPM) and the Y3 rat myeloma line.
  • Host Species
  • Rat
  • Type
  • IgG
  • Specificity
  • This antibody specifically recognize CD11b, also known as the integrin alpha M chain (MAC-1), which is a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages.
  • Clone
  • 5C6
  • Applications
  • IF, IHC-Fr, WB

Product Property

  • Purification
  • Protein A affinity purified
  • Buffer
  • PBS with preservative (0.02% Proclin 300)
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C

Applications

  • Application Notes
  • The mouse Itgam antibody has been reported in applications of Immunofluorescence, Immunohistochemistry-Frozen, Western Blot.

Target

  • Alternative Names
  • Itgam; integrin alpha M; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik; integrin alpha-M; CD11 antigen-like family member B; CD11B (p170); CR-3 alpha chain; Mac-1 alpha; cell surface glycoprotein MAC-1 alpha subunit; cell surface

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Itgam"

Single-domain Antibody

CAT Product Name Application Type
NABG-098 Recombinant Anti-Mouse Itgam VHH Single Domain Antibody CA, IP, IF, FuncS Llama VHH

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0708MZ Chicken Anti-ITGAM Polyclonal IgY ICC/IF Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1572CQ Recombinant Mouse Anti-ITGAM Antibody (CBRM1/5) FC, FuncS, IP, Neut IgG1, κ
NEUT-1574CQ Recombinant Rat Anti-Itgam Antibody (M1/70) ICC/IF, FC, FuncS, BL IgG2b, κ

Rabbit Monoclonal Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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