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Scorpion toxins anti-gp120 (SSX-L184)

The Scorpion toxin that bound gp120 was isolated from the library using Phage display techonology. After affinity maturation, Scorpion toxins variants were identified having affinities (KD=8 nM) for gp120 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Scorpion toxins
Origin
Scorpion toxins
Core Structure
α/β3 (25-40)
Variable Regions
Loop grafting or 4 aa
Target
gp120
Species Reactivity
HIV-1
Expression Host
E. coli
Affinity Constant
8 nM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
Scorpion toxins; Scorpion toxins; HIV1gp8
Entrez Gene ID
155971

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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