Scorpion toxins scaffold protein anti-HIV-1 gp120 (CAT#: SSX-L184)

The Scorpion toxin that bound gp120 was isolated from the library using Phage display techonology. After affinity maturation, Scorpion toxins variants were identified having affinities (KD=8 nM) for gp120 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


Specific Inquiry
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Specifications

  • Scaffold Name
  • Scorpion toxins
  • Origin
  • Scorpion toxins
  • Core Structure
  • α/β3 (25-40)
  • Variable Regions
  • Loop grafting or 4 aa
  • Target
  • gp120
  • Species Reactivity
  • HIV-1
  • Expression Host
  • E. coli
  • Affinity Constant
  • 8 nM
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • Scorpion toxins; Scorpion toxins; HIV1gp8

Downloads

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Human Antibody

Mouse Antibody

CAT Product Name Application Type
PABX-062-S (P) Recombinant Human Anti-gp120 Antibody scFv Fragment (PGT121-GL) WB, ELISA, FuncS scFv

Single-domain Antibody

CAT Product Name Application Type
PABX-002-VHH Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody (A12) ELISA llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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