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Src homology domain 3 (SH3) anti-ABL1 (SST-L192)

The Src homology domain 3 (SH3) that bound APTYPPPLPP (Abl-pep) was isolated from the library using Phage display techonology. After affinity maturation, SH2 variants were identified having affinities for APTYPPPLPP (Abl-pep) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Src homology domain 3 (SH3)
Origin
Abl-SH3 domain
Core Structure
Mainly β (~60)
Variable Regions
6 or 12 aa
Target
APTYPPPLPP (Abl-pep)
Species Reactivity
Human
Expression Host
E. coli
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
Abl-SH3 domain; Src homology domain 3 (SH3); ABL; JTK7; p150; c-ABL; v-abl; c-ABL1
Entrez Gene ID
25
UniProt ID
P00519

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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