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Src homology domain 3 (SH3) anti-Nef (SST-L193)

The Src homology domain 3 (SH3) that bound Nef was isolated from the library using Phage display techonology. After affinity maturation, SH3 variants were identified having affinities for Nef as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Src homology domain 3 (SH3)
Origin
Abl-SH3 domain
Core Structure
Mainly β (~60)
Variable Regions
6 or 12 aa
Target
Nef
Species Reactivity
SIV
Expression Host
E. coli
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
Abl-SH3 domain; Src homology domain 3 (SH3); nef protein; nef; SIVgp7
Entrez Gene ID
1490008
UniProt ID
Q02840

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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