Anti-Human C5 Recombinant Antibody (Tesidolumab) (CAT#: TAB-453CQ)

Recombinant monoclonal antibody to C5. Tesidolumab is a human monoclonal antibody that can be potentially used in the treatment of Choroiditis.


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SDS-PAGE

Figure 1 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in SDS-PAGE

Figure 1 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in SDS-PAGE

SDS-PAGE analysis of TAB-453CQ in non-reduced (right) and reduced (left) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.

SEC-HPLC

Figure 2 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in SEC-HPLC

Figure 2 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in SEC-HPLC

The purity of TAB-453CQ was greater than 95% as determined by HPLC.

ELISA

Figure 3 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in ELISA

Figure 3 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in ELISA

Sandwich ELISA analysis of TAB-453CQ was performed by coating with TAB-453CQ and Recombinant Human C5 (his tag).
The secondary antibody: HRP-Anti-His tag

WB

Figure 4 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in WB

Figure 4 Anti-Human C5 Recombinant Antibody (Tesidolumab) (TAB-453CQ) in WB

Western blot analysis of TAB-453CQ was performed by loading Recombinant Human C5 (His Tag).

TAB-453CQ incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane1: Reducing antigen (0.1 μg)
Lane2: Reducing antigen (0.3 μg)
Lane3: Reducing antigen (0.6 μg)


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1, λ2
  • Specificity
  • Human C5
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
  • Conjugate
  • Unconjugated
  • CAS
  • 1531594-08-7
  • Generic Name
  • Tesidolumab
  • UNII
  • 3FO6689MSD
  • Related Disease
  • Choroiditis

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • C5D; C5a; C5b; ECLZB; CPAMD4

Related Resources

  • Biosimilar Overview
  • Related Diseases
Please refer to Tesidolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tesidolumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Tesidolumab"

Afuco™ Anti-C5 ADCC Recombinant Antibody (Tesidolumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to C5. Tesidolumab is a human monoclonal antibody that can be potentially used in the treatment of Choroiditis.

See other products for "C5"

Humanized Antibody

CAT Product Name Application Type
TAB-084CL Human Anti-C5 Recombinant Antibody (TAB-084CL) ELISA, FuncS, Inhib Human IgG
TAB-1372CL Human Anti-C5 Recombinant Antibody (TAB-1372CL) Inhib, FuncS Humanized antibody
TAB-1373CL Human Anti-C5 Recombinant Antibody (TAB-1373CL) IB, CDC, Inhib Humanized IgG
TAB-1374CL Human Anti-C5 Recombinant Antibody (TAB-1374CL) ELISA, CDC, Inhib Humanized IgG
TAB-1375CL Human Anti-C5 Recombinant Antibody (TAB-1375CL) CDC, Inhib Humanized IgG

Recombinant Antibody

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-088CQ Mouse Anti-C5 Recombinant Antibody (clone CBL771) WB, Block, ELISA Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4104 Hi-Affi™ Rabbit Anti-C5 Recombinant Antibody (clone SI175DS) IHC-P Rabbit IgG

Single-domain Antibody

CAT Product Name Application Type
PABC-559 Recombinant Llama Anti-C5 Single Domain Antibody (Nb36) ELISA Llama VHH

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-453CQ Afuco™ Anti-C5 ADCC Recombinant Antibody (Tesidolumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-008 Afuco™ Anti-C5 ADCC Recombinant Antibody (Eculizumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody
AFC-TAB-436CQ Afuco™ Anti-C5 ADCC Recombinant Antibody (Olendalizumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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