Anti-Human F3 Recombinant Antibody (Tisotumab) (CAT#: TAB-473CQ)

Recombinant monoclonal antibody to F3. tisotumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.


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WB

Figure 1 Anti-Human F3 Antibody (TAB-473CQ) in WB

Figure 1 Anti-Human F3 Antibody (TAB-473CQ) in WB

Western blot analysis of TAB-473CQ was performed by loading human F3 protein in reduced condition Lane 1, Lane 2 and Lane 3 (0.1 μg, 0.3 μg and 0.6 μg respectively) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-473CQ (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 5000). Chemiluminescent detection was performed.

DB

Figure 2 Anti-Human F3 Antibody (TAB-473CQ) in DB

Figure 2 Anti-Human F3 Antibody (TAB-473CQ) in DB

Dot Blot analysis of TAB-473CQ was performed by coating with human F3 protein.

TAB-473CQ incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000)
NC: Negative control PC: Positive control

ELISA

Figure 3 Anti-Human F3 Antibody (TAB-473CQ) in ELISA

Figure 3 Anti-Human F3 Antibody (TAB-473CQ) in ELISA

ELISA analysis of TAB-473CQ was performed by coating with human F3 protein. Then blocked with BSA and incubated with TAB-473CQ. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1, κ
  • Specificity
  • Human F3
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Inhibition
  • Conjugate
  • Unconjugated
  • CAS
  • 1418731-10-8
  • Generic Name
  • Tisotumab
  • UNII
  • T41737F88A
  • Related Disease
  • Solid tumors

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

Related Resources

  • Biosimilar Overview
Please refer to Tisotumab Vedotin Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tisotumab Vedotin.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Tisotumab"

Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to F3. tisotumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.

See other products for "F3"

Recombinant Antibody

CAT Product Name Application Type
MOB-1092z Mouse Anti-F3 Recombinant Antibody (clone 18C8) WB, FC, ICC, FuncS Mouse IgG1
HPAB-0172CQ Human Anti-F3 Recombinant Antibody (HPAB-0172CQ) ELISA, FC, ADCC Chimeric (mouse/human) IgG1
HPAB-0173CQ Human Anti-F3 Recombinant Antibody (HPAB-0173CQ) ELISA, FC, ADCC Chimeric (mouse/human) IgG1, λ
FN-224CQ Mouse Anti-F3 Recombinant Antibody (clone HTF-1) FC, FuncS, ICC, IF, WB Mouse IgG1, κ
ZG-0661J Rabbit Anti-F3 Recombinant Antibody (clone 8B10) ELISA, WB, IHC Rabbit IgG

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-178LC Recombinant Anti-Human F3 Antibody (Non-glycosylated) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1226 Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) WB, IHC-P, ICC, IF Rabbit IgG

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0573CQ Mouse Anti-F3 Recombinant Antibody (clone hATR-5) ELISA, Inhib Mouse IgG4

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-473CQ Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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