This IgG specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities for IgG as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-950 | Human Anti-IgG Recombinant Antibody (clone YC176); scFv Fragment | ELISA | Human scFv |
FAMAB-0177-YC-S(P) | Mouse Anti-IgG Recombinant Antibody (clone 17F12); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0178-YC-S(P) | Mouse Anti-IgG Recombinant Antibody (clone 12.5H); scFv Fragment | ELISA, IF, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-092 | Recombinant Anti-Pig IGG VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
NABC-001 | Recombinant Anti-Rabbit IgG VHH Single Domain Antibody [Magnetic Beads] | IP | Llama VHH |
NABC-007 | Recombinant Anti-Rabbit IgG VHH Single Domain Antibody [Sepharose] | IP | Llama VHH |
NABC-008 | Recombinant Anti-Rabbit IgG VHH Single Domain Antibody [HRP] | WB, IHC-P, ELISA | Llama VHH |
HPAB-0727-YJ-VHH | Camelid Anti-Pig IgG Recombinant Single Domain Antibody (VI-16) | ELISA, WB, In vivo stable auxiliary | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0216MC | FITC-conjugated Sheep Anti-Rabbit IgG polyclonal Antibody | FACS, IHC-Fr, IHC-P, IM | |
MOB-0225MC | HRP-conjugated Rabbit Anti-Mouse IgG polyclonal Antibody | Dot, ELISA, IHC-Fr, IHC-P, IM, WB | |
FAMAB-1376CQ | Mouse Anti-IgG Recombinant Antibody (clone SB2H2) | IP, ELISA | Mouse IgG1 |
FAMAB-1377CQ | Mouse Anti-IgG Recombinant Antibody (clone NH3/130.5.2) | IP, WB | Mouse IgG1 |
FAMAB-1378CQ | Mouse Anti-IgG Recombinant Antibody (clone GT175) | WB, ELISA, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0485MZ | Chicken Anti-Rabbit IgG Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1764 | Rabbit Anti-IgG Recombinant Antibody (clone DS1764AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0177-YC-F(E) | Mouse Anti-IgG Recombinant Antibody (clone 17F12); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0178-YC-F(E) | Mouse Anti-IgG Recombinant Antibody (clone 12.5H); Fab Fragment | ELISA, IF, WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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