This transferrin specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities (KD=400 nM) for transferrin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-343 | Mouse Anti-TF Recombinant Antibody (clone 6A6); scFv Fragment | WB, ELISA, IF, FuncS | Mouse scFv |
HPAB-0232-YJ-S(P) | Rat Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0232-YJ-S(P)) | ELISA, FuncS | Rat scFv |
HPAB-0233-YJ-S(P) | Rat Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0233-YJ-S(P)) | ELISA, FC, FuncS | Rat scFv |
HPAB-2578LY-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-2578LY-S(P)) | ELISA | Humanized scfv |
HPAB-0717YY-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0717YY-S(P)) | ELISA, Inhib, WB, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-121 | Mouse Anti-TF Recombinant Antibody (clone 5G9); Fab Fragment | WB, IHC, IF, FuncS | Mouse Fab |
PFBC-122 | Human Anti-TF Recombinant Antibody (clone hATR-5); Fab Fragment | Block | Humanized Fab |
FAMAB-0318CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone PTF.02); Fab Fragment | ELISA, FC | Mouse Fab |
FAMAB-0319CQ-F(E) | Mouse Anti-TF Recombinant Antibody (clone TW4.20); Fab Fragment | ELISA, WB, FC, Inhib | Mouse Fab |
HPAB-0767-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0767-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0510CL | Mouse Anti-TF Recombinant Antibody (TAB-0510CL) | WB, IF, ELISA | Mouse IgG |
TAB-0510CL-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-0510CL-S(P)) | WB, IF, ELISA | Mouse scFv |
TAB-0510CL-F(E) | Mouse Anti-TF Recombinant Antibody; Fab Fragment (TAB-0510CL-F(E)) | WB, IF, ELISA | Mouse Fab |
TAB-598CT | Mouse Anti-TF Recombinant Antibody (TAB-598CT) | ELISA, FC | Mouse IgG1. κ |
TAB-598CT-S(P) | Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-598CT-S(P)) | ELISA, FC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-599CT | Anti-Human TF Recombinant Antibody (ATR-5) | ELISA, FC | Humanized antibody |
TAB-600CT | Anti-Human TF Recombinant Antibody (ATR-2) | ELISA, FC | Humanized antibody |
TAB-601CT | Anti-Human TF Recombinant Antibody (ATR-8) | ELISA, FC, BL | Humanized antibody |
TAB-599CT-S(P) | Anti-Human TF Recombinant Antibody scFv Fragment (ATR-5) | ELISA, FC | Humanized antibody |
TAB-600CT-S(P) | Anti-Human TF Recombinant Antibody scFv Fragment (ATR-2) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-602CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (3e10) | ELISA, BL | Human antibody |
TAB-603CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (3h2) | ELISA, BL | Human antibody |
TAB-604CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2c1) | ELISA, BL | Human antibody |
TAB-605CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2c11) | ELISA, BL | Human antibody |
TAB-606CT-F(E) | Anti-Human TF Recombinant Antibody Fab Fragment (2d3) | ELISA, BL | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-175LC | Recombinant Anti-Human TF Antibody (Non-glycosylated) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0860MZ | Chicken Anti-Transferrin Polyclonal IgY | ELISA | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1996CQ | Mouse Anti-TF Recombinant Antibody (clone HTF-14) | WB, Neut, ELISA, ICC, IF, IHC, IHC-P, RIA | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2022CQ | Mouse Anti-TF Recombinant Antibody (clone A68-B/A11) | ELISA, Inhib, IHC-P, IHC-Fr | Mouse IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3535 | Rabbit Anti-TF Recombinant Antibody (clone DS3535AB) | IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0767-CN | Human Anti-TF Recombinant Antibody (HPAB-0767-CN) | WB, ELISA, FC, IHC | Human IgG4 |
HPAB-0768-CN | Human Anti-TF Recombinant Antibody (HPAB-0768-CN) | WB, ELISA, FC, IHC | Human IgG4 |
HPAB-0769-CN | Human Anti-TF Recombinant Antibody (HPAB-0769-CN) | WB, ELISA, FC, IHC | Human IgG4 |
MRO-2239-CN | Rabbit Anti-TF Polyclonal Antibody (MRO-2239-CN) | WB, IF | Rabbit IgG |
HPAB-0232-YJ | Rat Anti-TF Recombinant Antibody (HPAB-0232-YJ) | IHC, FC, ELISA, IF, RIA, FuncS | Rat IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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