Products

Volociximab (TAB-077)

Recombinant monoclonal antibody to Integrin Integrin alpha 5 beta 1. Volociximab (also known as M200) is a chimeric monoclonal antibody jointly for treatment of a variety of advanced solid tumors. It binds to and inhibits the functional activity of α5β1 integrin.
It is thought to reduce metastases. Early results show potential in renal cell cancers.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Chimeric (mouse/human)
Type
IgG4
Specificity
Tested positive against native human antigen.
Species Reactivity
Human
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS NO.
558480-40-3
Generic Name
Volociximab
UNII
496K5Z02NW
M.W.
145.5 kDa
Related Disease
Unknown
Target
Alternative Names
Volociximab; 558480-40-3; M200; ITGA5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; integrin alpha-5; CD49e
Entrez Gene ID
3678
UniProt ID
P08648

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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