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Bispecific IgGs

Creative Biolabs provides world class bispecific IgG generation services based on the latest antibody engineering technology platform. Our scientists leverage the most advanced techniques to provide the most comprehensive bispecific antibodies (BsAbs) for cell and gene therapy market.

Figure: Structure of an IgG (Science, 2013)

Our antibody engineering platform offers unprecedented innovation of bispecific antibody development and manufacture. Creative Biolabs possesses unparalleled experience in those proven methods such as chemical cross-linking approach, hybrid-hybridoma technology and recombinant bispecific antibodies methods. In addition, with the rapid advances in bioengineering during the past decades, Creative Biolabs has also developed bispecific antibodies with its own genetic engineering platform to provide novel, best-in-class antibodies for diverse therapeutic application.

We provide customer purified and fully functional bispecific IgG antibodies in a wide variety as following: CrossMabTriomab, KIH (Knobs-in-holes) BsAb (KIH common LC; KIH assembly), Orthogonal Fab BsAb, DT-IgGs (dual-targeting), SEEDbody, LUZ-Y BsAb, DutaMab, Charge pair BsAb, Fab-arm exchange BsAb, κλ-body.

We can generate different classes of bispecific antibodies, which include:

Sliwkowski and Mellman. Antibody Therapeutics in Cancer. Science. 13 September 2013: Vol. 341 no. 6151 pp. 1192-1198.

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