As a global leading biotech company in antibody engineering field, Creative Biolabs provides superb dual action Fab (DAF) bispecific antibody (BsAb) services, including “two in one” bispecific antibodies and “four-in-one” tetraspecific antibodies.
Bispecific antibody can avoid the pairing problems between the heavy and the light chains by engineering the variable regions on a single kind of heavy and light chain to bind two different antigens. We can modify a monospecific antibody which is generated by phage display technique to bind another unrelated antigen. At the same time, this antibody can still keep its high binding affinity to the original antigen. Creative Biolabs offers dual action Fab (DAF) BsAbs, which allow differential but overlapped application of complementarity determining regions (CDRs) on the light and the heavy chain as the major binding domain for two targets. In addition, we also provide “four-in-one” antibodies based on CrossMab technique. The “four-in-one” antibody combines two different “two-in-one” antibodies targeting four antigens and shows increased activity compared with the “two-in-one” antibodies in vivo.
Creative Biolabs offers customers high-quality DAF bispecific antibodies based on our novel technology platforms. Our experts can design a suitable and creative strategy to promote your scientific and clinical research.
For research use only. Not intended for any clinical use.
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