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ALPI

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Proximal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (CACO-2)

Interaction

Homodimer.

Molecular function

Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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