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AMHR2
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Theca cells, Granulosa cells, granulocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEL, K-562)
Interaction
Interacts with type I receptor ACVR1.
Molecular function
Kinase, Receptor, Serine/threonine-protein kinase, Transferase
More Types Infomation
- Recombinant Anti-AMHR2 Antibody (MOB-56)
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- Derivation: Mouse
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
- Mouse Anti-AMHR2 Recombinant Antibody (clone NJH8) (MOB-0609MZ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IHC-P, WB
- Recombinant Anti-AMHR-II Antibody (MOB-57)
-
- Derivation: Mouse
- Type: IgG
- Application: WB, IP, FuncS
-
- Derivation: Human
- Type: IgG
- Application: IP, IF, Biosensors, FuncS
-
- Derivation: Human
- Type: IgG
- Application: ELISA, FuncS
- Recombinant Anti-AMHR-II Antibody scFv Fragment (MOB-57-S(P))
-
- Derivation: Mouse
- Type: scFv
- Application: FC, ELISA, FuncS
- Recombinant Human Anti-AMHR-II Antibody scFv Fragment (MHH-57-S(P))
-
- Derivation: Human
- Type: scFv
- Application: FC, WB, FuncS
- Recombinant Human Anti-AMHR2 Antibody scFv Fragment (MHH-56-S(P))
-
- Derivation: Human
- Type: scFv
- Application: FC, Neut, Funcs
- Recombinant Anti-AMHR2 Antibody scFv Fragment (MOB-56-S(P))
-
- Derivation: Mouse
- Type: scFv
- Application: FC, IP, FuncS
- Recombinant Anti-AMHR2 Antibody Fab Fragment (MOB-56-F(E))
-
- Derivation: Mouse
- Type: Fab
- Application: FC, WB, FuncS
- Recombinant Human Anti-AMHR-II Antibody Fab Fragment (MHH-57-F(E))
-
- Derivation: Human
- Type: Fab
- Application: WB, IF, FuncS
- Recombinant Human Anti-AMHR2 Antibody Fab Fragment (MHH-56-F(E))
-
- Derivation: Human
- Type: Fab
- Application: FC, ELISA, FuncS
- Recombinant Anti-AMHR-II Antibody Fab Fragment (MOB-57-F(E))
-
- Derivation: Mouse
- Type: Fab
- Application: FC, IP, FuncS
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Human Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0761CLV-F(E)) (TAB-0761CLV-F(E))
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, SPR, FuncS
- Human Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0760CLV-F(E)) (TAB-0760CLV-F(E))
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, SPR, FuncS
- Human Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0759CLV-F(E)) (TAB-0759CLV-F(E))
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, SPR, FuncS
- Human Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0758CLV-F(E)) (TAB-0758CLV-F(E))
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, SPR, FuncS
- Mouse Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0757CLV-F(E)) (TAB-0757CLV-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-AMHR2 Recombinant Antibody (TAB-0757CLV) (TAB-0757CLV)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC
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For Research Use Only. Not For Clinical Use.