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CCR5

CCR5 (C-C Motif Chemokine Receptor 5) is a Protein Coding gene. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Diseases associated with CCR5 include West Nile Virus and Type 1 Diabetes Mellitus 22. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and HIV Life Cycle.
    • Derivation: Humanized (from mouse)
    • Species Reactivity: Human
    • Type: IgG4
    • Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

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