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CD200R1
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hofbauer cells, Langerhans cells, granulocytes, Basal squamous epithelial cells, Hepatic stellate cells, T-cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enriched (HEL)
Interaction
CD200 and CD200R1 interact via their respective N-terminal Ig-like domains (By similarity). Interacts with Human herpesvirus 8 vOX2 protein. (Microbial infection) Interacts with human herpesvirus 8/HHV-8 protein vOX2/K14.
Molecular function
Receptor
More Types Infomation
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: WB, FuncS
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: WB, FuncS
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, WB, FC
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- Species Reactivity: Rat
- Type: Mouse IgG1
- Application: FC
- Mouse Anti-CD200R1 Recombinant Antibody (clone OX110) (FAMAB-1615CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG2a
- Application: FC
- Mouse Anti-CD200R1 Antibody (clone OX110), mRNA (FAMAB-1615CQ-mRNA)
-
- Species Reactivity: Mouse
- Mouse Anti-CD200R1 Recombinant Antibody (clone OX102) (FAMAB-1617CQ)
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- Species Reactivity: Rat
- Type: Mouse IgG1
- Application: IP, WB, Block, FC, IHC-Fr
- Human Anti-CD200R1 Antibody (clone OX108), mRNA (PABC-020-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD200R1 Antibody (clone OX102), mRNA (FAMAB-1617CQ-mRNA)
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- Species Reactivity: Rat
- Mouse Anti-CD200R1 Antibody (clone OX131), mRNA (FAMAB-1740CQ-mRNA)
-
- Species Reactivity: Mouse
- Mouse Anti-CD200R1 Recombinant Antibody (clone OX131) (FAMAB-1740CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG1
- Application: FC
- Anti-Human CD200R1 Recombinant Antibody Fab Fragment (huDX248) (TAB-1713CL-F(E))
-
- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
- Anti-Human CD200R1 Recombinant Antibody (TAB-111CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Anti-Human CD200R1 Recombinant Antibody scFv Fragment (huDX248) (TAB-1713CL-S(P))
-
- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
- Anti-Human CD200R1 Recombinant Antibody scFv Fragment (huDX182) (TAB-1712CL-S(P))
-
- Derivation: Humanized
- Type: Humanized antibody
- Application: FuncS, IP, Inhib
- Anti-Human CD200R1 Recombinant Antibody scFv Fragment (DX184) (TAB-1711CL-S(P))
-
- Application: FuncS
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human CD200R1 Recombinant Antibody (DX185) (TAB-1709CL)
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- Application: Inhib
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For Research Use Only. Not For Clinical Use.