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CD83

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene.
Protein class

CD markers

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Langerhans cells, B-cells, Macrophages, monocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Daudi, HDLM-2, U-698)

Interaction

Monomer.

More Types Infomation

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