Loading...
CDH2
CDH2 (Cadherin 2) is a Protein Coding gene. Diseases associated with CDH2 include Arrhythmogenic Right Ventricular Cardiomyopathy and Malignant Pleural Mesothelioma. Among its related pathways are N-cadherin signaling events and PAK Pathway. Gene Ontology (GO) annotations related to this gene include calcium ion binding and protein phosphatase binding. An important paralog of this gene is CDH4.
Protein class
CD markers, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Granulosa cells, Excitatory neurons, Oligodendrocyte precursor cells, Astrocytes, Inhibitory neurons, Muller glia cells)
Immune cell specificity
Group enriched (basophil, neutrophil)
Cell line specificity
Cell line enhanced (AF22, BJ, fHDF/TERT166)
Interaction
Homodimer (via extracellular region). Can also form heterodimers with other cadherins (via extracellular region). Dimerization occurs in trans, i. e. with a cadherin chain from another cell (By similarity). Interacts with CDCP1 (PubMed:16007225). Interacts with PCDH8; this complex may also include TAOK2 (By similarity). The interaction with PCDH8 may lead to internalization through TAOK2/p38 MAPK pathway (By similarity). Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. May interact with OBSCN (via protein kinase domain 2) (By similarity).
More Types Infomation
- Mouse Anti-CDH2 Recombinant Antibody (MOB-0141F) (MOB-0141F)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Mouse Anti-CDH2 Recombinant Antibody (MOB-0140F) (MOB-0140F)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Recombinant Human Anti-human CDH2 Antibody scFv Fragment (MHH-188-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, IHC, FuncS
- Mouse Anti-CDH2 Recombinant Antibody (clone A10-4) (MRO-1063-CN)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgM
- Application: WB, IF, IHC
- Rabbit Anti-CDH2 Recombinant Antibody (clone CBACN-393) (MRO-1059-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
- Rabbit Anti-CDH2 Polyclonal Antibody (MRO-2059-CN) (MRO-2059-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IP, RIA, FuncS
- Recombinant Human Anti-human CDH2 Antibody Fab Fragment (MHH-188-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: Neut, WB, FuncS
- Recombinant Anti-human CDH2 Antibody (MOB-188)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-human CDH2 Antibody scFv Fragment (MOB-188-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IF, FuncS
- Recombinant Anti-human CDH2 Antibody Fab Fragment (MOB-188-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FACS, FuncS
- Mouse Anti-CDH2 Recombinant Antibody (clone 8C11) (NEUT-444CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IF, WB, Block
- Rat Anti-CDH2 Recombinant Antibody (clone NCD-2) (NEUT-445CQ)
-
- Species Reactivity: Avian, Hamster, Human, Mouse, Chicken, Frog
- Type: Rat IgG2a
- Application: IF, IHC, IP, WB, Block, FC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
- Anti-Human CDH2 Recombinant Antibody Fab Fragment (B12) (TAB-1433CL-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
- Anti-Human CDH2 Recombinant Antibody Fab Fragment (A8) (TAB-1432CL-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
- Anti-Human CDH2 Recombinant Antibody Fab Fragment (A7) (TAB-1431CL-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
- Anti-Human CDH2 Recombinant Antibody Fab Fragment (A14) (TAB-1430CL-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
-
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IHC-P
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.