CEACAM5
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Class: Class I
Antigen: CEA
Antigen Species: Human
Peptide: YLSGADLNL
Conjugate: PE
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Class: Class I
Antigen: CEA
Antigen Species: Human
Peptide: YLSGADLNL
Conjugate: APC
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Class: Class I
Antigen: CEA
Antigen Species: Human
Peptide: YLSGANLNL
Conjugate: BV421
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Class: Class I
Antigen: CEA
Antigen Species: Human
Peptide: YLSGANLNL
Conjugate: APC
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1, κ
Application: WB, IP, IF, FC
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Species Reactivity: Human
Type: Mouse antibody
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
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Species Reactivity: Human
Type: Humanized scFv
Application: SPR, ELISA, FC
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Derivation: Chimeric (Mouse/Human)
Species Reactivity: Human
Type: Chimeric (Mouse/Human) IgG1
Application: Cyt, ELISA, FC, Inhib
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Derivation: Chimeric (Mouse/Human)
Species Reactivity: Human
Type: Chimeric (Mouse/Human) IgG1
Application: ELISA, FC
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized antibody
Application: ELISA
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Species Reactivity: Human
Type: Humanized antibody
Application: SPR, ELISA, FC
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Target: CEACAM5
Linker: CL3
Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Target: CEACAM5
Linker: CL1
Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Target: CEACAM5
Linker: CL2A
Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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Derivation: Mouse
Species Reactivity: Human
Type: IgG1
Application: IF, IP, Neut, FuncS, ELISA, FC, IHC
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Species Reactivity: Human
Application: Cytotoxicity assay, Functional assay
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Species Reactivity: Human
Application: Cytotoxicity assay, Functional assay
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For Research Use Only. Not For Clinical Use.