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CGB3
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (BEWO)
Interaction
Heterodimer of a common alpha chain identical in LH, FSH, TSH and HCG and a unique beta chain distinct in each of the hormones.
Molecular function
Hormone
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC
- Human Anti-CGB3 Recombinant Antibody (clone AB4) (FAMAB-1329CQ)
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, ELISA, IHC
- Human Anti-CGB3 Recombinant Antibody (clone 3A2) (FAMAB-1328CQ)
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P
- Human Anti-CGB3 Recombinant Antibody (clone B11); scFv Fragment (HPAB-1674-FY-F(E))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-CGB3 Recombinant Antibody (clone B11) (HPAB-1674-FY)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
- Choriogonadotropin alfa (TP-035CL)
-
- CAS number: 177073-44-8
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Human Anti-CGB3 Recombinant Antibody (clone B11); Fab Fragment (HPAB-1674-FY-S(P))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Human Anti-CGB3 Recombinant Antibody (clone YC018); Fab Fragment (NS-036CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.