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CKM
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
Protein class
Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SCLC-21H)
Interaction
Dimer of identical or non-identical chains, which can be either B (brain type) or M (muscle type). With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
Molecular function
Kinase, Transferase
More Types Infomation
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- Species Reactivity: Human
- Application: IHC-P, WB
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- Species Reactivity: Human
- Application: I-ELISA, IHC-Fr, WB
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- Species Reactivity: Mouse
- Type: Mouse antibody
- Application: WB
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: FC, Neut, Funcs
-
- Species Reactivity: Human
- Application: WB
-
- Species Reactivity: Human
- Application: WB
- Recombinant Mouse Anti-CKM Antibody (MAK33) (PABL-377)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, FuncS
- Recombinant Human Anti-human CKM Antibody Fab Fragment (MHH-213-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
-
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, FuncS
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, FuncS
- Recombinant Human Anti-human CKM Antibody scFv Fragment (MHH-213-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, FuncS
- Recombinant Anti-human CKM Antibody scFv Fragment (MOB-213-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-human CKM Antibody Fab Fragment (MOB-213-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, Nert, FuncS
- Recombinant Anti-human CKM Antibody (MOB-213)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
-
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, FuncS
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
- Mouse Anti-CKM Antibody (clone MAK33), mRNA (PABL-377-mRNA)
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- Species Reactivity: Human
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.