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CTSH

CTSH (Cathepsin H) is a Protein Coding gene. Diseases associated with CTSH include Thyroid Crisis and Intermittent Explosive Disorder. Among its related pathways are Innate Immune System and Surfactant metabolism. Gene Ontology (GO) annotations related to this gene include protein complex binding and peptidase activity. An important paralog of this gene is CTSK.
Protein class

Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Alveolar cells type 2, Proximal tubular cells)

Immune cell specificity

Group enriched (classical monocyte, myeloid DC, intermediate monocyte, non-classical monocyte, memory B-cell, naive B-cell)

Cell line specificity

Cell line enhanced (CAPAN-2, HaCaT, HDLM-2, OE19, RT4)

Interaction

Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds.

Molecular function

Hydrolase, Protease, Thiol protease

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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