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CXCL11

C-X-C motif chemokine 11 is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) andInterferon-gamma-inducible protein 9 (IP-9). It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lungand low expression levels were in small intestine, placenta and prostate.
Protein class

Human disease related genes

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Macrophages, Prostatic glandular cells, Exocrine glandular cells, Alveolar cells type 1, Basal respiratory cells, Proximal enterocytes, Distal enterocytes, Basal prostatic cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG)

Interaction

Interacts with TNFAIP6 (via Link domain).

Molecular function

Cytokine

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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