ENG
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Class: Class I
Antigen: ENG
Antigen Species: Human
Peptide: LLTAALWYV
Conjugate: PE
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Class: Class I
Antigen: ENG
Antigen Species: Human
Peptide: LLTAALWYV
Conjugate: APC
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Class: Class I
Antigen: ENG
Antigen Species: Human
Peptide: LLTAALWYV
Conjugate: FITC
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Class: Class I
Antigen: ENG
Antigen Species: Human
Peptide: LLTAALWYV
Conjugate: Unconjugated
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: IF, IHC, WB
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Species Reactivity: Human
Type: Mouse antibody
Application: IHC
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Species Reactivity: Human
Type: Mouse IgG1
Application: WB, Neut
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Derivation: Phage display library
Species Reactivity: Human
Type: Rabbit IgG
Application: WB, IHC-P, IP, FC
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Species Reactivity: Mouse
Type: Rabbit IgG
Application: WB, IF, IHC, FC
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Species Reactivity: Human
Type: Mouse IgG
Application: FC
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Species Reactivity: Human
Type: Mouse Fab
Application: FC
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Species Reactivity: Human
Type: Mouse IgG
Application: FC, Apop
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Species Reactivity: Human
Type: Mouse Fab
Application: FC, Apop
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Derivation: Humanized
Species Reactivity: Human
Type: Human scFv
Application: Apop
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Species Reactivity: Human
Type: Human IgG1
Application: ELISA, FC
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Species Reactivity: Human
Type: Human Fab
Application: ELISA, FC
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Species Reactivity: Human
Type: Mouse scFv
Application: FC
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Species Reactivity: Human
Type: Human Fab
Application: ELISA, FC
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Species Reactivity: Human
Type: Mouse scFv
Application: FC, Apop
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Species Reactivity: Cynomolgus monkey CD105
Type: Fully human antibody
Application: FuncS
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For Research Use Only. Not For Clinical Use.