Disease related genes, Human disease related genes
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXL3) composed of CUL1, SKP1, RBX1 and FBXL3 (By similarity). Interacts with CRY1 and CRY2 (phosphorylated) (PubMed:17463251). Interacts with HDAC3 (By similarity). Interacts with KDM8 (By similarity).
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For Research Use Only. Not For Clinical Use.