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HLA-DR

HLA-DR antigen is released from the cell surface by proteolytic digestion and is detectable in serum and other body fluids. Determination of the soluble form (s-HLA-DR) may be an important diagnostic marker for lymphoproliferative and autoimmune diseases, and blocking the interaction of s- HLA-DR with Tirc7 receptors on the surface of CD4+ T cells may affect their activation.

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