CD markers, Disease related genes, Human disease related genes
Membrane
Cell type enhanced (Kupffer cells, monocytes, Langerhans cells, Plasma cells, Macrophages, NK-cells, T-cells, Extravillous trophoblasts, dendritic cells)
Low immune cell specificity
Cell line enhanced (Daudi, HDLM-2, Karpas-707, RPMI-8226)
Interacts with IL10 (PubMed:16982608, 15837194). Interacts with IL10RB (PubMed:16982608). Interacts (via its cytoplasmic domain) with JAK1 (via N-terminus) (PubMed:12133952). Interacts with BTRC; this interaction leads to IL10RA ubiquitination and subsequent degradation (PubMed:22087322). Interacts with STAT3 (By similarity). (Microbial infection) Interacts with human cytomegalovirus protein IL10. (Microbial infection) Interacts with Epstein-Barr virus protein IL10.
Receptor
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For Research Use Only. Not For Clinical Use.