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IL20RA

This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Endometrial ciliated cells, Glandular and luminal cells, Breast glandular cells, Muller glia cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CAPAN-2, HaCaT, OE19, RT4, SH-SY5Y, T-47d)

Interaction

Heterodimer with IL20RB and heterodimer with IL10RB.

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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