Cancer-related genes, CD markers, Plasma proteins
Membrane
Cell type enhanced (Extravillous trophoblasts, Endothelial cells, Hepatic stellate cells)
Immune cell enhanced (neutrophil)
Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME, U-87 MG)
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. Interacts with CIB1. ITGA5:ITGB1 interacts with CCN3. ITGA5:ITGB1 interacts with FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 interacts with IL1B (PubMed:29030430). ITGA5:ITGB1 interacts with ACE2 (PubMed:33102950). Interacts with ANGPT2 (PubMed:32908006). (Microbial infection) Integrin ITGA5:ITGB1 interacts with human metapneumovirus fusion protein. (Microbial infection) Integrin ITGA5:ITGB1 interacts with human parvovirus B19 capsid proteins. (Microbial infection) Interacts with HIV-1 Tat. (Microbial infection) ITGA5:ITGB1 interacts with SARS coronavirus-2/SARS-CoV-2 spike protein.
Host cell receptor for virus entry, Integrin, Receptor
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For Research Use Only. Not For Clinical Use.