Loading...
Integrin α5β1
This is a fully human, fragment crystalizable (Fc)-engineered IgG1 mAb, which specifically neutralizes α5 and binds the Fcγ receptors (FcγR) with enhanced affinity. In vitro, PF-5412 potently inhibited α5β1-mediated intracellular signaling, cell adhesion, migration, and endothelial cell (EC) tubulogenesis. The dual mechanism of action and robust antitumor efficacy of PF-5412 support its clinical development for the treatment of a broad spectrum of human malignancies.
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: Neut, FuncS
- Recombinant Mouse Anti-GPIIb Antibody Fab Fragment (314.1) (PABX-066-F (E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, FuncS
- Recombinant Mouse Anti-GPIIb Antibody scFv Fragment (314.1) (PABX-066-S (P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, FuncS
-
- Derivation: Hamster
- Species Reactivity: Human
- Type: Hamster IgG
- Application: ELISA
-
- Derivation: Human
- Type: Human IgG
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12IgG1TM); scFv Fragment (HPAB-0788-CN-S(P))
-
- Derivation: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 1F2.2B7); scFv Fragment (HPAB-0787-CN-S(P))
-
- Derivation: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12); scFv Fragment (HPAB-0786-CN-S(P))
-
- Derivation: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody; Fab Fragment (HPAB-0394-CN-F(E)) (HPAB-0394-CN-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
-
- Derivation: Chimeric (hamster/human)
- Species Reactivity: Human
- Type: Chimeric (hamster/human) IgG
- Application: ELISA, FuncS
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12IgG1TM); Fab Fragment (HPAB-0788-CN-F(E))
-
- Derivation: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 1F2.2B7); Fab Fragment (HPAB-0787-CN-F(E))
-
- Derivation: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12); Fab Fragment (HPAB-0786-CN-F(E))
-
- Derivation: Human
- Type: Human Fab
- Application: ELISA, FC
-
- Derivation: Human
- Type: Human IgG4, κ
- Application: ELISA, FC
- Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12) (HPAB-0786-CN)
-
- Derivation: Human
- Type: Human IgG4, κ
- Application: ELISA, FC
-
- Derivation: Hamster
- Species Reactivity: Human
- Type: Hamster scFv
- Application: ELISA
- Human Anti-Integrin α5β1 Recombinant Antibody (clone h18C12.v2.1); Fab Fragment (HPAB-J0148-YC-F(E))
-
- Derivation: Chimeric (hamster/human)
- Species Reactivity: Human
- Type: Chimeric (hamster/human) Fab
- Application: ELISA, Inhib, FuncS
- Anti-human Integrin α5β1 Fab Fragment (MOR04055) (TAB-722LC-F(E))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
- Anti-human Integrin α5β1 Fab Fragment (5B11) (TAB-721LC-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
- Anti-human Integrin α5β1 Fab Fragment (3C5) (TAB-720LC-F(E))
-
- Type: Human antibody
- Application: ELISA, FC
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.