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KITLG
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, RAS pathway related proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Basal squamous epithelial cells, Collecting duct cells, Inhibitory neurons, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CACO-2, SK-BR-3)
Interaction
Homodimer, non-covalently linked (Probable). Heterotetramer with KIT, binding two KIT molecules; thereby mediates KIT dimerization and subsequent activation by autophosphorylation.
Molecular function
Growth factor
More Types Infomation
- Recombinant Human Anti-human KITLG Antibody scFv Fragment (MHH-601-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: RIA, ELISA, FuncS
- Recombinant Anti-human KITLG Antibody scFv Fragment (MOB-601-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, Neut, Biosensors, FuncS
- Recombinant Anti-human KITLG Antibody Fab Fragment (MOB-601-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, ELISA, FuncS
- Recombinant Anti-human KITLG Antibody (MOB-601)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, FuncS
-
- Species Reactivity: Human
- Application: ELISA
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, ICC/IF, IHC-P, WB
- Recombinant Human Anti-human KITLG Antibody Fab Fragment (MHH-601-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: FC, ELISA, FuncS
- Mouse Anti-KITLG Recombinant Antibody; Fab Fragment (TAB-0475CL-F(E)) (TAB-0475CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Block, FuncS
- Human Anti-KITLG Recombinant Antibody (clone A2-G8) (HPAB-0299CQ)
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- Derivation: Human
- Species Reactivity: Human, Monkey, Rat
- Type: Human IgG
- Application: ELISA, FC, Neut
- Mouse Anti-KITLG Recombinant Antibody (TAB-0475CL) (TAB-0475CL)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Block, FuncS
- Human Anti-KITLG Recombinant Antibody (clone A2-G8); scFv Fragment (HPAB-0299CQ-S(P))
-
- Derivation: Human
- Species Reactivity: Human, Monkey, Rat
- Type: Human scFv
- Application: ELISA, FC, Neut
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
- Human Anti-KITLG Recombinant Antibody (clone A2-G8); Fab Fragment (HPAB-0299CQ-F(E))
-
- Derivation: Human
- Species Reactivity: Human, Monkey, Rat
- Type: Human Fab
- Application: ELISA, FC, Neut
- Mouse Anti-KITLG Recombinant Antibody; scFv Fragment (TAB-0475CL-S(P)) (TAB-0475CL-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Block, FuncS
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For Research Use Only. Not For Clinical Use.