Cancer-related genes, Human disease related genes
Intracellular
Low cell type specificity
Low immune cell specificity
Cell line enhanced (BEWO)
Interacts with MDM2 (PubMed:16163388, PubMed:19838211, PubMed:32300648). Interacts with TP53, TP73 and USP2. Found in a trimeric complex with USP2, MDM2 and MDM4. Interacts (phosphorylated) with YWHAG; negatively regulates MDM4 activity toward TP53.
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For Research Use Only. Not For Clinical Use.