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MS4A1
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1,κ
- Application: WB, ELISA, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, Activ, Agonist, IF, WB, Cyt, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
- Anti-CD20 (1F5)-vcMMAE ADC (ADC-023LCT)
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- Target: CD20
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD20 (clone Batl206)-SMCC-MDC ADC (ADC-160CL)
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- Target: CD20
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: MDC (maytansinol)
- Anti-CD20-mc-vc-PABC-MMAE ADC (ADC-187LZY)
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- Target: CD20
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-CD20-CL2E-SN-38 ADC (ADC-022LCT)
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- Target: CD20
- Linker: CL2E
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- Anti-CD20-MCC-DM1 ADC (ADC-186LZY)
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- Target: CD20
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD20-CL2A-SN-38 ADC (ADC-021LCT)
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- Target: CD20
- Linker: CL2A
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- Anti-CD20-SPP-DM1 ADC (ADC-185LZY)
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- Target: CD20
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD20 (clone hA20)-SN-38 ADC (ADC-125CL)
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- Target: CD20
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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For Research Use Only. Not For Clinical Use.