MTX
Methotrexate (MTX) is a clinically important antifolate drug, which competitively inhibits dihydrofolate reductase (DHFR), thereby impairing folate production. Folate is necessary for the de novo synthesis of thymidine, required for DNA synthesis. Folate is also required for purine base synthesis of DNA, RNA, thymidylates, and proteins. Thus, methotrexate impairs synthesis of thymidine and other metabolites crucial for cell proliferation.
Derivation: Mouse
Type: Mouse IgG
Application: WB, ELISA, FuncS
Compare
Derivation: Human
Type: IgG
Application: ELISA, IP, FuncS
Compare
Derivation: Llama
Type: Llama VHH
Application: ELISA, WB
Compare
Derivation: Mouse
Type: scFv
Application: ELISA, WB, IF, FuncS
Compare
Derivation: Mouse
Type: Fab
Application: WB, IP, FuncS
Compare
Derivation: Mouse
Type: IgG
Application: ELISA, WB, FuncS
Compare
Derivation: Mouse
Type: Mouse Fab
Application: WB, ELISA, FuncS
Compare
Derivation: Human
Type: Fab
Application: IP, Neut, FuncS
Compare
Derivation: Mouse
Type: Mouse scFv
Application: WB, ELISA, FuncS
Compare
Derivation: Human
Type: scFv
Application: ELISA, WB, FuncS
Compare
Type: Mouse scFv
Application: ECL
Compare
Species Reactivity: Human
Type: Mouse Fab
Application: ELISA
Compare
Type: Mouse Fab
Application: ECL
Compare
Type: Mouse IgG
Application: ECL
Compare
Type: Mouse IgG
Application: ECL
Compare
Type: Mouse IgG
Application: ECL
Compare
Species Reactivity: Human
Type: Mouse IgG
Application: ELISA
Compare
Type: Mouse Fab
Application: ECL
Compare
Type: Mouse Fab
Application: ECL
Compare
Type: Mouse scFv
Application: ECL
Compare
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.