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NPW

The product of this gene is processed into 23-and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog.
Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Group enriched (Endometrial stromal cells, Enteroendocrine cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Group enriched (NB-4, PC-3, RPMI-8226, SCLC-21H)

Molecular function

Neuropeptide

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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