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PDGFC
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain.
Protein class
RAS pathway related proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Granulosa cells, Astrocytes, Microglial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (fHDF/TERT166, hTERT-RPE1, U-138 MG)
Interaction
Homodimer; disulfide-linked. Interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts (via CUB domain) with PLAT (via kringle domain).
Molecular function
Developmental protein, Growth factor, Mitogen
More Types Infomation
- Recombinant Anti-human PDGFC Antibody scFv Fragment (MOB-758-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
- Recombinant Anti-human PDGFC Antibody Fab Fragment (MOB-758-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FacS, FuncS
- Recombinant Anti-human PDGFC Antibody (MOB-758)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Dot, FuncS
- Recombinant Human Anti-human PDGFC Antibody Fab Fragment (MHH-758-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IF, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IP, IF, Biosensors, FuncS
- Recombinant Human Anti-human PDGFC Antibody scFv Fragment (MHH-758-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Recombinant Mouse Anti-PDGFC Antibody (5F12) (NEUT-1843CQ)
-
- Species Reactivity: Human
- Type: IgG2
- Application: WB, Neut
- Recombinant Mouse Anti-PDGFC Antibody (CBL152) (NEUT-1844CQ)
-
- Species Reactivity: Human
- Type: IgG2
- Application: Neut
- Recombinant Mouse Anti-PDGFC Antibody (CBL634) (NEUT-1845CQ)
-
- Species Reactivity: Human
- Type: IgG2b
- Application: Neut
- Mouse Anti-PDGFC Recombinant Antibody; scFv Fragment (HPAB-0013-LS-S(P)) (HPAB-0013-LS-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Inhib
- Mouse Anti-PDGFC Recombinant Antibody; Fab Fragment (TAB-0986CL-F(E)) (TAB-0986CL-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; Fab Fragment (TAB-0985CL-F(E)) (TAB-0985CL-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; Fab Fragment (TAB-0984CL-F(E)) (TAB-0984CL-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; Fab Fragment (TAB-0983CL-F(E)) (TAB-0983CL-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; Fab Fragment (TAB-0982CL-F(E)) (TAB-0982CL-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; scFv Fragment (TAB-0984CL-S(P)) (TAB-0984CL-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; scFv Fragment (TAB-0983CL-S(P)) (TAB-0983CL-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody; scFv Fragment (TAB-0982CL-S(P)) (TAB-0982CL-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody (TAB-0985CL) (TAB-0985CL)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
- Mouse Anti-PDGFC Recombinant Antibody (TAB-0984CL) (TAB-0984CL)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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