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PF4V1

The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Cholangiocytes, Macrophages, Enteroendocrine cells, Club cells, Theca cells)

Immune cell specificity

Group enriched (basophil, neutrophil)

Cell line specificity

Cell line enhanced (EFO-21)

Interaction

Homotetramer.

Molecular function

Cytokine, Heparin-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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