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PGF

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.
Protein class

Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, RAS pathway related proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Syncytiotrophoblasts, Extravillous trophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (BEWO, HUVEC TERT2)

Interaction

Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF. Isoform PlGF-3 is found both as homodimer and as monomer.

Molecular function

Developmental protein, Growth factor, Heparin-binding, Mitogen

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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