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PSCA
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Protein class
Cancer-related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Gastric mucus-secreting cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CAPAN-2, HeLa, OE19, RT4)
Interaction
Interacts with CHRNA4.
More Types Infomation
- PE-A*02:01/Human PSCA (AILALLPAL) MHC Tetramer (MHC-LC021)
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- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AILALLPAL
- Conjugate: PE
- APC-A*02:01/Human PSCA (AILALLPAL) MHC Tetramer (MHC-LC022)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AILALLPAL
- Conjugate: APC
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AILALLPAL
- Conjugate: BV421
- PE-A*02:01/Human PSCA (QLGEQCWTV) MHC Tetramer (MHC-CN1165)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: QLGEQCWTV
- Conjugate: PE
- APC-A*02:01/Human PSCA (QLGEQCWTV) MHC Tetramer (MHC-CN1166)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: QLGEQCWTV
- Conjugate: APC
- FITC-A*02:01/Human PSCA (QLGEQCWTV) MHC Tetramer (MHC-CN1167)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: QLGEQCWTV
- Conjugate: FITC
- A*02:01/Human PSCA (QLGEQCWTV) MHC Tetramer (MHC-CN1168)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: QLGEQCWTV
- Conjugate: Unconjugated
- APC-H-2Db/Human PSCA (AQMNNRDCL) MHC Tetramer (MHC-CN0023)
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- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AQMNNRDCL
- Conjugate: APC
- PE-H-2Db/Human PSCA (AQMNNRDCL) MHC Tetramer (MHC-CN0024)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AQMNNRDCL
- Conjugate: PE
-
- Class: Class I
- Antigen: Prostate stem cell antigen
- Antigen Species: Human
- Peptide: VLLALLMAGL
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Class: Class I
- Antigen: Prostate Stem Cell Antigen (PSCA)
- Antigen Species: Human
- Peptide: ALQPGTALL
- Conjugate: Unlabeled, Biotin, R-PE, APC
- A*02:01/Human PSCA (AILALLPALL) MHC Pentamer (MHC-YF696)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: AILALLPALL
- Conjugate: Unlabeled, Biotin, R-PE, APC
- A*02:01/Human PSCA (LLCYSCKAQV) MHC Pentamer (MHC-YF697)
-
- Class: Class I
- Antigen: PSCA
- Antigen Species: Human
- Peptide: LLCYSCKAQV
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Class: Class I
- Antigen: PSCA (51A)
- Antigen Species: Human
- Peptide: QLGEQCWTV
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Species Reactivity: Human
- Application: IHC-P, WB
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, IF
-
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
- Anti-Human PSCA Recombinant Antibody Fab Fragment (6D1) (TAB-261CT-F(E))
-
- Species Reactivity: Human
- Type: Human antibody
- Application: IHC, FC
- Anti-Human PSCA Recombinant Antibody Fab Fragment (6E4) (TAB-260CT-F(E))
-
- Species Reactivity: Human
- Type: Human antibody
- Application: IHC, FC
-
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
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For Research Use Only. Not For Clinical Use.