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PTGDR2
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Protein class
CD markers, G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Smooth muscle cells, granulocytes, Fibroblasts, Langerhans cells, Endothelial cells, Cone photoreceptor cells, Intestinal goblet cells)
Immune cell specificity
Group enriched (eosinophil, basophil)
Cell line specificity
Cell line enhanced (HEL, Hep G2, HMC-1, K-562, MOLT-4, NB-4)
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
- Recombinant Anti-Human PTGDR2 Antibody (MOB-2771z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
- Recombinant Anti-Human PTGDR2 Antibody scFv Fragment (MOB-2771z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
- Recombinant Anti-Human PTGDR2 Antibody Fab Fragment (MOB-2771z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, IF, FuncS
- Anti-Human PTGDR2 Recombinant Antibody Fab Fragment (31A5) (TAB-070MZ-F(E))
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody Fab Fragment (3C12) (TAB-069MZ-F(E))
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody Fab Fragment (8B1) (TAB-068MZ-F(E))
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- Application: FC
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- Type: Humanized antibody
- Application: FC
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- Type: Humanized antibody
- Application: FC
- Anti-Human PTGDR2 Therapeutical Antibody (TAB-741CL)
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- Species Reactivity: Human
- Type: Antibody
- Anti-Human PTGDR2 Recombinant Antibody scFv Fragment (31A5) (TAB-070MZ-S(P))
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody scFv Fragment (3C12) (TAB-069MZ-S(P))
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody scFv Fragment (8B1) (TAB-068MZ-S(P))
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody scFv Fragment (19A2) (TAB-067MZ-S(P))
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- Species Reactivity: Cynomolgus
- Application: FC
- Human Anti-PTGDR2 Recombinant Antibody; Fab Fragment (HPAB-0685YY-F(E)) (HPAB-0685YY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
- Anti-Human PTGDR2 Recombinant Antibody Fab Fragment (19A2) (TAB-067MZ-F(E))
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- Species Reactivity: Cynomolgus
- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody (31A5) (TAB-070MZ)
-
- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody (3C12) (TAB-069MZ)
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody (8B1) (TAB-068MZ)
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- Application: FC
- Anti-Human PTGDR2 Recombinant Antibody (19A2) (TAB-067MZ)
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- Species Reactivity: Cynomolgus
- Application: FC, IF
- Human Anti-PTGDR2 Recombinant Antibody (HPAB-0685YY) (HPAB-0685YY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: FC, Inhib, Antagonist, ELISA
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For Research Use Only. Not For Clinical Use.