Cancer-related genes, Disease related genes, Enzymes, Potential drug targets
Membrane
Cell type enhanced (Basal squamous epithelial cells, Undifferentiated cells, Intestinal goblet cells)
Not detected in immune cells
Cell line enhanced (A549, CACO-2, Hep G2, OE19)
Interacts with AKAP8L, NONO and SFPQ (PubMed:18313049, PubMed:18655028). Interacts with FZD5 (PubMed:22895187). Identified in a complex composed of RNF43, LGR5 and RSPO1 (PubMed:23756651). Interacts with RSPO2 (PubMed:29769720). Interacts with LMBR1L (By similarity).
Developmental protein, Transferase
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For Research Use Only. Not For Clinical Use.