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RXFP1

The anti-LGR7 antibodies have antibody-dependent cell-mediated cytotoxicity (ADCC) activity and complement-dependent cytotoxicity (CDC) activity against LGR7-expressing cells. The anti-LGR7 antibodies are useful for diagnosis, prevention, and treatment of primary and metastatic ovarian clear cell adenocarcinoma.
Protein class

G-protein coupled receptors, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Glandular and luminal cells, Excitatory neurons, Endometrial ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (EFO-21, HEL, RPTEC TERT1, THP-1)

Interaction

Interacts with C1QTNF8.

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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