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SIGLEC6

This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
Protein class

CD markers

Predicted location

Membrane, Secreted (different isoforms)

Single cell type specificity

Group enriched (Syncytiotrophoblasts, Cytotrophoblasts, granulocytes)

Immune cell specificity

Group enriched (plasmacytoid DC, memory B-cell, basophil, naive B-cell)

Cell line specificity

Cell line enriched (HMC-1)

Interaction

Interacts with LEP.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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