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SIRPG

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein class

CD markers

Predicted location

Membrane

Single cell type specificity

Group enriched (Early spermatids, T-cells, Late spermatids)

Immune cell specificity

Immune cell enhanced (T-reg)

Cell line specificity

Cell line enhanced (hTERT-RPE1, JURKAT, NB-4, RT4, THP-1)

Interaction

Interacts with CD47.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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