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THY1

This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants.
Protein class

CD markers, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Smooth muscle cells, Fibroblasts, Proximal tubular cells, Endometrial stromal cells, Excitatory neurons, Muller glia cells, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC diff, BJ, BJ hTERT+, fHDF/TERT166)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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