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TRO

The anti-KIAA1114 antibody specifically binds to an extracellular domain of a KIAA1114 protein, specifically reacts with various cancer cell lines and remarkably represses metastasis of cancer in vivo in a lung metastasis animal model using a KIAA1114 over-expression cancer cell line. Therefore, the anti-KIAA1114 antibody can be effectively used for the prevention or treatment of cancer- particularly metastatic cancer, which is caused by KIAA1114 over-expression.
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Oligodendrocyte precursor cells, Excitatory neurons, Granulosa cells, Oligodendrocytes, Astrocytes)

Immune cell specificity

Immune cell enhanced (NK-cell)

Cell line specificity

Cell line enhanced (AF22, SH-SY5Y, SuSa)

Interaction

Directly binds bystin, and indirectly tastin.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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